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Generation of germ cells from pluripotent stem cells in mammals

BACKGROUND: The germ cell lineage transmits genetic and epigenetic information to the next generation. Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been studied extensively. Recently, in vitro models of PGC induction have been established in the mouse. Many att...

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Detalles Bibliográficos
Autores principales: Hayashi, Masafumi, Kawaguchi, Takamasa, Durcova‐Hills, Gabriela, Imai, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902460/
https://www.ncbi.nlm.nih.gov/pubmed/29692667
http://dx.doi.org/10.1002/rmb2.12077

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