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Interleukin-15-Cultured Dendritic Cells Enhance Anti-Tumor Gamma Delta T Cell Functions through IL-15 Secretion
Dendritic cell (DC) vaccination can be an effective post-remission therapy for acute myeloid leukemia (AML). Yet, current DC vaccines do not encompass the ideal stimulatory triggers for innate gamma delta (γδ) T cell anti-tumor activity. Promoting type 1 cytotoxic γδ T cells in patients with AML is,...
Autores principales: | Van Acker, Heleen H., Anguille, Sébastien, De Reu, Hans, Berneman, Zwi N., Smits, Evelien L., Van Tendeloo, Viggo F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902500/ https://www.ncbi.nlm.nih.gov/pubmed/29692776 http://dx.doi.org/10.3389/fimmu.2018.00658 |
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