Cargando…

μ-opioid receptor system mediates reward processing in humans

The endogenous μ-opioid receptor (MOR) system regulates motivational and hedonic processing. We tested directly whether individual differences in MOR are associated with neural reward responses to food pictures in humans. We scanned 33 non-obese individuals with positron emission tomography (PET) us...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nummenmaa, Lauri, Saanijoki, Tiina, Tuominen, Lauri, Hirvonen, Jussi, Tuulari, Jetro J., Nuutila, Pirjo, Kalliokoski, Kari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902580/ https://www.ncbi.nlm.nih.gov/pubmed/29662095 http://dx.doi.org/10.1038/s41467-018-03848-y

Ejemplares similares

Cerebral μ-opioid and CB(1) receptor systems have distinct roles in human feeding behavior
por: Kantonen, Tatu, et al.
Publicado: (2021)

Neural Circuits for Cognitive Appetite Control in Healthy and Obese Individuals: An fMRI Study
por: Tuulari, Jetro J., et al.
Publicado: (2015)

Preoperative brain μ-opioid receptor availability predicts weight development following bariatric surgery in women
por: Karlsson, Henry K., et al.
Publicado: (2021)

Dorsal Striatum and Its Limbic Connectivity Mediate Abnormal Anticipatory Reward Processing in Obesity
por: Nummenmaa, Lauri, et al.
Publicado: (2012)

Lowered endogenous mu-opioid receptor availability in subclinical depression and anxiety
por: Nummenmaa, Lauri, et al.
Publicado: (2020)

Seasonal Variation in the Brain μ-Opioid Receptor Availability
por: Sun, Lihua, et al.
Publicado: (2021)

Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB(1) receptor availability
por: Kantonen, Tatu, et al.
Publicado: (2021)

μ-opioid receptor availability is associated with sex drive in human males
por: Nummenmaa, Lauri, et al.
Publicado: (2021)

Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery
por: Karlsson, Henry K., et al.
Publicado: (2021)

Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese
por: Tuulari, Jetro J., et al.
Publicado: (2013)

Erratum. Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese. Diabetes 2013;62:2747–2751
por: Tuulari, Jetro J., et al.
Publicado: (2017)

Endogenous Opioid Release After Orgasm in Man: A Combined PET/Functional MRI Study
por: Jern, Patrick, et al.
Publicado: (2023)

Association of CNR1 gene and cannabinoid 1 receptor protein in the human brain
por: Pak, Kyoungjune, et al.
Publicado: (2022)

Magia: Robust Automated Image Processing and Kinetic Modeling Toolbox for PET Neuroinformatics
por: Karjalainen, Tomi, et al.
Publicado: (2020)

Brain free fatty acid uptake is elevated in morbid obesity, and is irreversible 6 months after bariatric surgery: A positron emission tomography study
por: Rebelos, Eleni, et al.
Publicado: (2020)

Brain insulin sensitivity is linked to body fat distribution—the positron emission tomography perspective
por: Rebelos, Eleni, et al.
Publicado: (2020)

Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance
por: Hirvonen, Jussi, et al.
Publicado: (2011)

Brain substrate metabolism and ß‐cell function in humans: A positron emission tomography study
por: Rebelos, Eleni, et al.
Publicado: (2020)

Walking Speed and Brain Glucose Uptake are Uncoupled in Patients with Multiple Sclerosis
por: Kindred, John H., et al.
Publicado: (2015)

μ-Opioid Receptors on Distinct Neuronal Populations Mediate Different Aspects of Opioid Reward-Related Behaviors
por: Severino, Amie L., et al.
Publicado: (2020)

[(11)C]carfentanil PET imaging for studying the peripheral opioid system in vivo: effect of photoperiod on mu-opioid receptor availability in brown adipose tissue
por: Sun, Lihua, et al.
Publicado: (2022)

Obesity risk is associated with brain glucose uptake and insulin resistance
por: Pekkarinen, Laura, et al.
Publicado: (2022)

Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort
por: Rebelos, Eleni, et al.
Publicado: (2021)

Secretin modulates appetite via brown adipose tissue-brain axis
por: Sun, Lihua, et al.
Publicado: (2023)

Just watching the game ain't enough: striatal fMRI reward responses to successes and failures in a video game during active and vicarious playing
por: Kätsyri, Jari, et al.
Publicado: (2013)

Brain dopamine receptor system is not altered in obesity: Bayesian and frequentist meta‐analyses
por: Pak, Kyoungjune, et al.
Publicado: (2023)

The Obesity Risk SNP (rs17782313) near the MC4R Gene Is Not Associated with Brain Glucose Uptake during Insulin Clamp—A Study in Finns
por: Rebelos, Eleni, et al.
Publicado: (2021)

Neural responses to biological motion distinguish autistic and schizotypal traits
por: Hudson, Matthew, et al.
Publicado: (2023)

Effect of nitric oxide synthase inhibition on the exchange of glucose and fatty acids in human skeletal muscle
por: Heinonen, Ilkka, et al.
Publicado: (2013)

Brain glucose uptake is associated with endogenous glucose production in obese patients before and after bariatric surgery and predicts metabolic outcome at follow‐up
por: Rebelos, Eleni, et al.
Publicado: (2018)

Segmentation of Striatal Brain Structures from High Resolution PET Images
por: Farinha, Ricardo J. P. C., et al.
Publicado: (2009)

Resistance Training Increases White Matter Density in Frail Elderly Women
por: Bucci, Marco, et al.
Publicado: (2023)

m.3243A>G Mutation in Mitochondrial DNA Leads to Decreased Insulin Sensitivity in Skeletal Muscle and to Progressive β-Cell Dysfunction
por: Lindroos, Markus M., et al.
Publicado: (2009)

GRK Mediates μ-Opioid Receptor Plasma Membrane Reorganization
por: Gondin, Arisbel B., et al.
Publicado: (2019)

Circulating neurofilament is linked with morbid obesity, renal function, and brain density
por: Rebelos, Eleni, et al.
Publicado: (2022)

Pattern recognition reveals sex‐dependent neural substrates of sexual perception
por: Putkinen, Vesa, et al.
Publicado: (2023)

Dopamine D2/3- and μ-opioid receptor antagonists reduce cue-induced responding and reward impulsivity in humans
por: Weber, S C, et al.
Publicado: (2016)

Dentate gyrus μ-opioid receptor-mediated neurogenic processes are associated with alterations in morphine self-administration
por: Zhang, Haolin, et al.
Publicado: (2019)

Quantitative Detection of µ Opioid Receptor: Western Blot Analyses Using µ Opioid Receptor Knockout Mice
por: Kasai, Shinya, et al.
Publicado: (2011)

Human μ Opioid Receptor Models with Evaluation of the Accuracy Using the Crystal Structure of the Murine μ Opioid Receptor
por: Perez-Aguilar, Jose Manuel, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9rfhvj5ertn7phang9lgg8lkl6