Cargando…
HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development
Glycolytic reprogramming is a typical feature of many cancers; however, key regulators of glucose metabolism reengineering are poorly understood, especially in cutaneous squamous cell carcinoma (cSCC). Here, Homeobox A9 (HOXA9), a direct target of onco-miR-365, is identified to be significantly down...
Autores principales: | Zhou, Liang, Wang, Yinghui, Zhou, Meijuan, Zhang, Ying, Wang, Pengfei, Li, Xiaoxing, Yang, Jing, Wang, Hongmei, Ding, Zhenhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902613/ https://www.ncbi.nlm.nih.gov/pubmed/29662084 http://dx.doi.org/10.1038/s41467-018-03914-5 |
Ejemplares similares
-
HOXA9 Transcriptionally Promotes Apoptosis and Represses Autophagy by Targeting NF-κB in Cutaneous Squamous Cell Carcinoma
por: Han, Shuo, et al.
Publicado: (2019) -
Loss of BAX by miR-365 Promotes Cutaneous Squamous Cell Carcinoma Progression by Suppressing Apoptosis
por: Zhou, Liang, et al.
Publicado: (2017) -
PRMT5 Prevents Cardiomyocyte Hypertrophy via Symmetric Dimethylating HoxA9 and Repressing HoxA9 Expression
por: Cai, Sidong, et al.
Publicado: (2020) -
HIF-1α or HOTTIP/CTCF Promotes Head and Neck Squamous Cell Carcinoma Progression and Drug Resistance by Targeting HOXA9
por: Sun, Qiang, et al.
Publicado: (2020) -
HIF-1α or HOTTIP/CTCF Promotes Head and Neck Squamous Cell Carcinoma Progression and Drug Resistance by Targeting HOXA9
por: Sun, Qiang, et al.
Publicado: (2022)