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Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

Depression is a polygenic trait that causes extensive periods of disability. Previous genetic studies have identified common risk variants which have progressively increased in number with increasing sample sizes of the respective studies. Here, we conduct a genome-wide association study in 322,580...

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Detalles Bibliográficos
Autores principales: Howard, David M., Adams, Mark J., Shirali, Masoud, Clarke, Toni-Kim, Marioni, Riccardo E., Davies, Gail, Coleman, Jonathan R. I., Alloza, Clara, Shen, Xueyi, Barbu, Miruna C., Wigmore, Eleanor M., Gibson, Jude, Hagenaars, Saskia P., Lewis, Cathryn M., Ward, Joey, Smith, Daniel J., Sullivan, Patrick F., Haley, Chris S., Breen, Gerome, Deary, Ian J., McIntosh, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902628/
https://www.ncbi.nlm.nih.gov/pubmed/29662059
http://dx.doi.org/10.1038/s41467-018-03819-3