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Pridopidine Reverses Phencyclidine-Induced Memory Impairment

Pridopidine is in clinical trials for Huntington's disease treatment. Originally developed as a dopamine D(2) receptor (D(2)R) ligand, pridopidine displays about 100-fold higher affinity for the sigma-1 receptor (sigma-1R). Interestingly, pridopidine slows disease progression and improves motor...

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Detalles Bibliográficos
Autores principales:	Sahlholm, Kristoffer, Valle-León, Marta, Fernández-Dueñas, Víctor, Ciruela, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902730/ https://www.ncbi.nlm.nih.gov/pubmed/29692729 http://dx.doi.org/10.3389/fphar.2018.00338

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