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Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()()

BACKGROUND: The various guidelines clearly mention the treatment strategies for in patient of acute myocardial infarction (MI) presenting more than 24 h from symptom onset (recent myocardial infarction, RMI). However, the appropriate timing of reperfusion for RMI is unclear. METHODS: We retrospectiv...

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Autores principales: Mizuguchi, Yukio, Shibutani, Hiroki, Hashimoto, Sho, Yamada, Takeshi, Taniguchi, Norimasa, Nakajima, Shunsuke, Hata, Tetsuya, Takahashi, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902826/
https://www.ncbi.nlm.nih.gov/pubmed/29455786
http://dx.doi.org/10.1016/j.ihj.2017.06.015
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author Mizuguchi, Yukio
Shibutani, Hiroki
Hashimoto, Sho
Yamada, Takeshi
Taniguchi, Norimasa
Nakajima, Shunsuke
Hata, Tetsuya
Takahashi, Akihiko
author_facet Mizuguchi, Yukio
Shibutani, Hiroki
Hashimoto, Sho
Yamada, Takeshi
Taniguchi, Norimasa
Nakajima, Shunsuke
Hata, Tetsuya
Takahashi, Akihiko
author_sort Mizuguchi, Yukio
collection PubMed
description BACKGROUND: The various guidelines clearly mention the treatment strategies for in patient of acute myocardial infarction (MI) presenting more than 24 h from symptom onset (recent myocardial infarction, RMI). However, the appropriate timing of reperfusion for RMI is unclear. METHODS: We retrospectively evaluated 525 consecutive MI patients who underwent percutaneous coronary intervention (PCI) in our hospital between January 2008 and December 2012. RESULTS: Sixty RMI patients were more frequently associated with cardiac complications such as myocardial rupture (3.3% vs. 0%; p < 0.01), ventricular septal rupture (3.3% vs. 0.4%; p < 0.05), and congestive heart failure (15% vs. 2.6%; p < 0.001) than 272 consecutive ST-elevation myocardial infarction (STEMI) patients. Of the 60 RMI patients, 33 (55.0%) underwent PCI within 7 days (early-PCI group) and 27 (45.0%) underwent PCI after 7 days (late-PCI group). Left ventricular ejection fraction measured by echocardiography at second hospital day was similar between the groups. The early-PCI group was more significantly associated with cardiogenic shock and heart failure and more frequently required intra-aortic balloon pumping (24.2% vs. 3.7%; p < 0.05) than the late-PCI group. There were no significant differences in 30-day mortality, cardiac complications, and major cardiac events during long-term follow-up (12–36 months) between the groups. CONCLUSION: RMI patients had a higher incidence of cardiac complications than AMI patients. Clinical outcomes were similar between patients undergoing early revascularization and those undergoing late revascularization, although the former group included a higher proportion of patients with severe cardiac failure.
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spelling pubmed-59028262019-01-01 Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()() Mizuguchi, Yukio Shibutani, Hiroki Hashimoto, Sho Yamada, Takeshi Taniguchi, Norimasa Nakajima, Shunsuke Hata, Tetsuya Takahashi, Akihiko Indian Heart J Original Article BACKGROUND: The various guidelines clearly mention the treatment strategies for in patient of acute myocardial infarction (MI) presenting more than 24 h from symptom onset (recent myocardial infarction, RMI). However, the appropriate timing of reperfusion for RMI is unclear. METHODS: We retrospectively evaluated 525 consecutive MI patients who underwent percutaneous coronary intervention (PCI) in our hospital between January 2008 and December 2012. RESULTS: Sixty RMI patients were more frequently associated with cardiac complications such as myocardial rupture (3.3% vs. 0%; p < 0.01), ventricular septal rupture (3.3% vs. 0.4%; p < 0.05), and congestive heart failure (15% vs. 2.6%; p < 0.001) than 272 consecutive ST-elevation myocardial infarction (STEMI) patients. Of the 60 RMI patients, 33 (55.0%) underwent PCI within 7 days (early-PCI group) and 27 (45.0%) underwent PCI after 7 days (late-PCI group). Left ventricular ejection fraction measured by echocardiography at second hospital day was similar between the groups. The early-PCI group was more significantly associated with cardiogenic shock and heart failure and more frequently required intra-aortic balloon pumping (24.2% vs. 3.7%; p < 0.05) than the late-PCI group. There were no significant differences in 30-day mortality, cardiac complications, and major cardiac events during long-term follow-up (12–36 months) between the groups. CONCLUSION: RMI patients had a higher incidence of cardiac complications than AMI patients. Clinical outcomes were similar between patients undergoing early revascularization and those undergoing late revascularization, although the former group included a higher proportion of patients with severe cardiac failure. Elsevier 2018 2017-06-30 /pmc/articles/PMC5902826/ /pubmed/29455786 http://dx.doi.org/10.1016/j.ihj.2017.06.015 Text en © 2017 Published by Elsevier B.V. on behalf of Cardiological Society of India. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Mizuguchi, Yukio
Shibutani, Hiroki
Hashimoto, Sho
Yamada, Takeshi
Taniguchi, Norimasa
Nakajima, Shunsuke
Hata, Tetsuya
Takahashi, Akihiko
Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()()
title Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()()
title_full Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()()
title_fullStr Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()()
title_full_unstemmed Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()()
title_short Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()()
title_sort examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a japanese single-center retrospective study()()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902826/
https://www.ncbi.nlm.nih.gov/pubmed/29455786
http://dx.doi.org/10.1016/j.ihj.2017.06.015
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