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Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()()
BACKGROUND: The various guidelines clearly mention the treatment strategies for in patient of acute myocardial infarction (MI) presenting more than 24 h from symptom onset (recent myocardial infarction, RMI). However, the appropriate timing of reperfusion for RMI is unclear. METHODS: We retrospectiv...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902826/ https://www.ncbi.nlm.nih.gov/pubmed/29455786 http://dx.doi.org/10.1016/j.ihj.2017.06.015 |
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author | Mizuguchi, Yukio Shibutani, Hiroki Hashimoto, Sho Yamada, Takeshi Taniguchi, Norimasa Nakajima, Shunsuke Hata, Tetsuya Takahashi, Akihiko |
author_facet | Mizuguchi, Yukio Shibutani, Hiroki Hashimoto, Sho Yamada, Takeshi Taniguchi, Norimasa Nakajima, Shunsuke Hata, Tetsuya Takahashi, Akihiko |
author_sort | Mizuguchi, Yukio |
collection | PubMed |
description | BACKGROUND: The various guidelines clearly mention the treatment strategies for in patient of acute myocardial infarction (MI) presenting more than 24 h from symptom onset (recent myocardial infarction, RMI). However, the appropriate timing of reperfusion for RMI is unclear. METHODS: We retrospectively evaluated 525 consecutive MI patients who underwent percutaneous coronary intervention (PCI) in our hospital between January 2008 and December 2012. RESULTS: Sixty RMI patients were more frequently associated with cardiac complications such as myocardial rupture (3.3% vs. 0%; p < 0.01), ventricular septal rupture (3.3% vs. 0.4%; p < 0.05), and congestive heart failure (15% vs. 2.6%; p < 0.001) than 272 consecutive ST-elevation myocardial infarction (STEMI) patients. Of the 60 RMI patients, 33 (55.0%) underwent PCI within 7 days (early-PCI group) and 27 (45.0%) underwent PCI after 7 days (late-PCI group). Left ventricular ejection fraction measured by echocardiography at second hospital day was similar between the groups. The early-PCI group was more significantly associated with cardiogenic shock and heart failure and more frequently required intra-aortic balloon pumping (24.2% vs. 3.7%; p < 0.05) than the late-PCI group. There were no significant differences in 30-day mortality, cardiac complications, and major cardiac events during long-term follow-up (12–36 months) between the groups. CONCLUSION: RMI patients had a higher incidence of cardiac complications than AMI patients. Clinical outcomes were similar between patients undergoing early revascularization and those undergoing late revascularization, although the former group included a higher proportion of patients with severe cardiac failure. |
format | Online Article Text |
id | pubmed-5902826 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59028262019-01-01 Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()() Mizuguchi, Yukio Shibutani, Hiroki Hashimoto, Sho Yamada, Takeshi Taniguchi, Norimasa Nakajima, Shunsuke Hata, Tetsuya Takahashi, Akihiko Indian Heart J Original Article BACKGROUND: The various guidelines clearly mention the treatment strategies for in patient of acute myocardial infarction (MI) presenting more than 24 h from symptom onset (recent myocardial infarction, RMI). However, the appropriate timing of reperfusion for RMI is unclear. METHODS: We retrospectively evaluated 525 consecutive MI patients who underwent percutaneous coronary intervention (PCI) in our hospital between January 2008 and December 2012. RESULTS: Sixty RMI patients were more frequently associated with cardiac complications such as myocardial rupture (3.3% vs. 0%; p < 0.01), ventricular septal rupture (3.3% vs. 0.4%; p < 0.05), and congestive heart failure (15% vs. 2.6%; p < 0.001) than 272 consecutive ST-elevation myocardial infarction (STEMI) patients. Of the 60 RMI patients, 33 (55.0%) underwent PCI within 7 days (early-PCI group) and 27 (45.0%) underwent PCI after 7 days (late-PCI group). Left ventricular ejection fraction measured by echocardiography at second hospital day was similar between the groups. The early-PCI group was more significantly associated with cardiogenic shock and heart failure and more frequently required intra-aortic balloon pumping (24.2% vs. 3.7%; p < 0.05) than the late-PCI group. There were no significant differences in 30-day mortality, cardiac complications, and major cardiac events during long-term follow-up (12–36 months) between the groups. CONCLUSION: RMI patients had a higher incidence of cardiac complications than AMI patients. Clinical outcomes were similar between patients undergoing early revascularization and those undergoing late revascularization, although the former group included a higher proportion of patients with severe cardiac failure. Elsevier 2018 2017-06-30 /pmc/articles/PMC5902826/ /pubmed/29455786 http://dx.doi.org/10.1016/j.ihj.2017.06.015 Text en © 2017 Published by Elsevier B.V. on behalf of Cardiological Society of India. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Mizuguchi, Yukio Shibutani, Hiroki Hashimoto, Sho Yamada, Takeshi Taniguchi, Norimasa Nakajima, Shunsuke Hata, Tetsuya Takahashi, Akihiko Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()() |
title | Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()() |
title_full | Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()() |
title_fullStr | Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()() |
title_full_unstemmed | Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()() |
title_short | Examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a Japanese single-center retrospective study()() |
title_sort | examination of the appropriate timing of reperfusion therapy for recent myocardial infarction: a japanese single-center retrospective study()() |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902826/ https://www.ncbi.nlm.nih.gov/pubmed/29455786 http://dx.doi.org/10.1016/j.ihj.2017.06.015 |
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