RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas

BACKGROUND: Precursor T-cell lymphoblastic lymphomas (T-LBL) are rare aggressive hematological malignancies that mainly develop in children. As in other cancers, the loss of cell cycle control plays a prominent role in the pathogenesis in these malignancies that is primarily attributed to loss of CD...

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Detalles Bibliográficos
Autores principales: López-Nieva, Pilar, Fernández-Navarro, Pablo, Vaquero-Lorenzo, Concepción, Villa-Morales, María, Graña-Castro, Osvaldo, Cobos-Fernández, María Ángeles, López-Lorenzo, José Luis, Llamas, Pilar, González-Sanchez, Laura, Sastre, Isabel, Pollan, Marina, Malumbres, Marcos, Santos, Javier, Fernández-Piqueras, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902834/
https://www.ncbi.nlm.nih.gov/pubmed/29661169
http://dx.doi.org/10.1186/s12885-018-4304-y

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