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Presence of novel triple mutations in the pvdhfr from Plasmodium vivax in Mangaluru city area in the southwestern coastal region of India
BACKGROUND: Genes encoding dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) are the targets of sulfadoxine–pyrimethamine (SP) present in artemisinin based combination therapy (ACT; artesunate + sulfadoxine pyrimethamine) for Plasmodium falciparum. Although SP is generally not used...
Autores principales: | Joy, Shiny, Ghosh, Susanta K., Achur, Rajeshwara N., Gowda, D. Channe, Surolia, Namita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902849/ https://www.ncbi.nlm.nih.gov/pubmed/29661235 http://dx.doi.org/10.1186/s12936-018-2316-3 |
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