Takotsubo syndrome

Takotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium. Coronary angiography...

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Detalles Bibliográficos
Autores principales: Gupta, Sanjiv, Gupta, Madan Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902911/
https://www.ncbi.nlm.nih.gov/pubmed/29455773
http://dx.doi.org/10.1016/j.ihj.2017.09.005
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author Gupta, Sanjiv
Gupta, Madan Mohan
author_facet Gupta, Sanjiv
Gupta, Madan Mohan
author_sort Gupta, Sanjiv
collection PubMed
description Takotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium. Coronary angiography reveals normal epicardial arteries with no obstruction or spasm. NT-ProBNP maybe remarkably elevated. Regional wall motion akinesia (RWMA) of left ventricle extends beyond the territory of one coronary artery. Reduced left ventricle ejection fraction (LVEF) and RWMA recover in 6–12 weeks. Prognosis is generally good. Recent meta-analysis shows in-hospital mortality of 1–4.5% and recurrence rate of 5–10% during five year follow-up.
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spelling pubmed-59029112019-01-01 Takotsubo syndrome Gupta, Sanjiv Gupta, Madan Mohan Indian Heart J Review Article Takotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium. Coronary angiography reveals normal epicardial arteries with no obstruction or spasm. NT-ProBNP maybe remarkably elevated. Regional wall motion akinesia (RWMA) of left ventricle extends beyond the territory of one coronary artery. Reduced left ventricle ejection fraction (LVEF) and RWMA recover in 6–12 weeks. Prognosis is generally good. Recent meta-analysis shows in-hospital mortality of 1–4.5% and recurrence rate of 5–10% during five year follow-up. Elsevier 2018 2017-09-13 /pmc/articles/PMC5902911/ /pubmed/29455773 http://dx.doi.org/10.1016/j.ihj.2017.09.005 Text en © 2017 Published by Elsevier B.V. on behalf of Cardiological Society of India. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Gupta, Sanjiv
Gupta, Madan Mohan
Takotsubo syndrome
title Takotsubo syndrome
title_full Takotsubo syndrome
title_fullStr Takotsubo syndrome
title_full_unstemmed Takotsubo syndrome
title_short Takotsubo syndrome
title_sort takotsubo syndrome
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902911/
https://www.ncbi.nlm.nih.gov/pubmed/29455773
http://dx.doi.org/10.1016/j.ihj.2017.09.005
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