Valproic acid sensitizes metformin-resistant human renal cell carcinoma cells by upregulating H3 acetylation and EMT reversal

BACKGROUND: Metformin (Met) is a widely available diabetic drug and shows suppressed effects on renal cell carcinoma (RCC) metabolism and proliferation. Laboratory studies in RCC suggested that metformin has remarkable antitumor activities and seems to be a potential antitumor drug. But the facts th...

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Detalles Bibliográficos
Autores principales: Wei, Muyun, Mao, Shaowei, Lu, Guoliang, Li, Liang, Lan, Xiaopeng, Huang, Zhongxian, Chen, Yougen, Zhao, Miaoqing, Zhao, Yueran, Xia, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902941/
https://www.ncbi.nlm.nih.gov/pubmed/29665787
http://dx.doi.org/10.1186/s12885-018-4344-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902941/
https://www.ncbi.nlm.nih.gov/pubmed/29665787
http://dx.doi.org/10.1186/s12885-018-4344-3

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