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Pretreatment with nimodipine reduces incidence of POCD by decreasing calcineurin mediated hippocampal neuroapoptosis in aged rats

BACKGROUND: Calcineurin (CaN) having a high expression in hippocampal neurons is closely related to apoptosis. Pretreatment with nimodipine can lower the apoptosis rate of hippocampal neuron to reduce the incidence of postoperative cognitive dysfunction (POCD). However, the relationship between cere...

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Detalles Bibliográficos
Autores principales:	Zhang, Qi, Li, Yanan, Bao, Yongjuan, Yin, Chunping, Xin, Xi, Guo, Yangyang, Gao, Fang, Huo, Shuping, Wang, Xiuli, Wang, Qiujun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902967/ https://www.ncbi.nlm.nih.gov/pubmed/29661144 http://dx.doi.org/10.1186/s12871-018-0501-0

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