Cargando…

Targeted delivery of immuno-RNase may improve cancer therapy

BACKGROUND: Immunotoxins are typical therapeutic drugs that can target cancer cells. They exploit the affinity of specific monoclonal antibodies or ligands to cancer cells to deliver a conjugated protein toxin to target sites, thus, attacking the cancer cells. METHODS: The immuno-RNase, Onc-V3, show...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Miaonan, Sun, Liankun, Sun, Dejun, Zhang, Chunmei, Li, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902972/ https://www.ncbi.nlm.nih.gov/pubmed/29686536 http://dx.doi.org/10.1186/s12935-018-0546-7

Ejemplares similares

The B7H4-PDL1 classifier stratifies immuno-phenotype in cervical cancer
por: Chen, Lingyan, et al.
Publicado: (2022)

PGM5 is a promising biomarker and may predict the prognosis of colorectal cancer patients
por: Sun, Yifan, et al.
Publicado: (2019)

Noninvasive prenatal testing for chromosome aneuploidies and subchromosomal microdeletions/microduplications in a cohort of 42,910 single pregnancies with different clinical features
por: Chen, Yibo, et al.
Publicado: (2019)

Updates in the Development of ImmunoRNases for the Selective Killing of Tumor Cells
por: Jordaan, Sandra, et al.
Publicado: (2018)

A novel fully human anti-NCL immunoRNase for triple-negative breast cancer therapy
por: D'Avino, Chiara, et al.
Publicado: (2016)

The Anti-Cancer Potency and Mechanism of a Novel Tumor-Activated Fused Toxin, DLM
por: Sun, Dejun, et al.
Publicado: (2015)

Mammaglobin as a potential molecular target for breast cancer drug delivery
por: Zuo, Lian, et al.
Publicado: (2009)

A novel fully human antitumour immunoRNase targeting ErbB2-positive tumours
por: Borriello, M, et al.
Publicado: (2011)

Target delivery of MYCN siRNA by folate-nanoliposomes delivery system in a metastatic neuroblastoma model
por: Zhu, Qiqi, et al.
Publicado: (2013)

FOXD3 may be a new cellular target biomarker as a hypermethylation gene in human ovarian cancer
por: Luo, Gui-fang, et al.
Publicado: (2019)

NEIL3 may act as a potential prognostic biomarker for lung adenocarcinoma
por: Zhao, Cui, et al.
Publicado: (2021)

Ten-gene signature reveals the significance of clinical prognosis and immuno-correlation of osteosarcoma and study on novel skeleton inhibitors regarding MMP9
por: Li, Weihang, et al.
Publicado: (2021)

MicroRNA-492 expression promotes the progression of hepatic cancer by targeting PTEN
por: Jiang, Jianxin, et al.
Publicado: (2014)

CD98hc has a pivotal role in maintaining the immuno-barrier integrity of basal layer cells in esophageal epithelium
por: Ye, Hao, et al.
Publicado: (2022)

Single-nucleotide polymorphism rs17548629 in RIPK1 gene may be associated with lung cancer in a young and middle-aged Han Chinese population
por: Yang, Shimin, et al.
Publicado: (2020)

Specific growth suppression of human cancer cells by targeted delivery of Dictyostelium mitochondrial ribosomal protein S4
por: Chida, Junji, et al.
Publicado: (2014)

Targeted nanobody complex enhanced photodynamic therapy for lung cancer by overcoming tumor microenvironment
por: Zhang, Qing, et al.
Publicado: (2020)

Targeting REV7 effectively reverses 5-FU and oxaliplatin resistance in colorectal cancer
por: Sun, Xianjun, et al.
Publicado: (2020)

Analysis of therapeutic targets and prognostic biomarkers of CXC chemokines in cervical cancer microenvironment
por: Kong, Weina, et al.
Publicado: (2021)

Antitumor responses in gastric cancer by targeting B7H3 via chimeric antigen receptor T cells
por: Sun, Fengqiang, et al.
Publicado: (2022)

Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing
por: Xie, Huilin, et al.
Publicado: (2018)

Identification of autophagy-related risk signatures for the prognosis, diagnosis, and targeted therapy in cervical cancer
por: Meng, Dan, et al.
Publicado: (2021)

Exosomal circRNA as a novel potential therapeutic target for multiple myeloma-related myocardial damage
por: Sun, Runjie, et al.
Publicado: (2021)

Immune signature-based hepatocellular carcinoma subtypes may provide novel insights into therapy and prognosis predictions
por: Zheng, Qiuxian, et al.
Publicado: (2021)

miR-502-5p affects gastric cancer progression by targeting PD-L1
por: You, Wendao, et al.
Publicado: (2020)

High CTHRC1 expression may be closely associated with angiogenesis and indicates poor prognosis in lung adenocarcinoma patients
por: Chen, Yangshan, et al.
Publicado: (2019)

Pregnant trauma patients may be at increased risk of mortality compared to nonpregnant women of reproductive age: trends and outcomes over 10 years at a level I trauma center
por: Maxwell, Bryan G, et al.
Publicado: (2020)

miR-133a targets YES1 to reduce cisplatin resistance in ovarian cancer by regulating cell autophagy
por: Zhou, Yang, et al.
Publicado: (2022)

MicroRNA-378-5p suppresses cell proliferation and induces apoptosis in colorectal cancer cells by targeting BRAF
por: Wang, Zhenlei, et al.
Publicado: (2015)

Targeting Akt by SC66 triggers GSK-3β mediated apoptosis in colon cancer therapy
por: Liu, Yeying, et al.
Publicado: (2019)

Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1’s pro-metastatic functions in esophageal cancer
por: Li, Gang, et al.
Publicado: (2020)

Association of human XPA rs1800975 polymorphism and cancer susceptibility: an integrative analysis of 71 case–control studies
por: Yuan, Maoxi, et al.
Publicado: (2020)

Curcumin reduces mitomycin C resistance in breast cancer stem cells by regulating Bcl-2 family-mediated apoptosis
por: Zhou, Qian-Mei, et al.
Publicado: (2017)

Circulating tumor microemboli (CTM) and vimentin+ circulating tumor cells (CTCs) detected by a size-based platform predict worse prognosis in advanced colorectal cancer patients during chemotherapy
por: Zhang, Dejun, et al.
Publicado: (2017)

B-cell receptor-guided delivery of peptide-siRNA complex for B-cell lymphoma therapy
por: Migliaccio, Nunzia, et al.
Publicado: (2015)

MiR–20a-5p promotes radio-resistance by targeting Rab27B in nasopharyngeal cancer cells
por: Huang, Dabing, et al.
Publicado: (2017)

Prognostic value of the systemic immune-inflammation index in patients with breast cancer: a meta-analysis
por: Zhang, Yantao, et al.
Publicado: (2020)

microRNA-30b inhibits cell invasion and migration through targeting collagen triple helix repeat containing 1 in non-small cell lung cancer
por: Chen, Shanshan, et al.
Publicado: (2015)

Efficacy and challenges of a culturally relevant intervention to improve attitudes to aging
por: Seah, Siang Joo, et al.
Publicado: (2019)

A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy
por: Cheung, Chun Hei Antonio, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_hqudgle9spccol5qr7hn1380f2