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Formulation of cilostazol spherical agglomerates by crystallo-co-agglomeration technique and optimization using design of experimentation

INTRODUCTION: Spherical agglomeration is one of the novel techniques for improvement of flow and dissolution properties of drugs. Cilostazol is a biopharmaceutics classification system Class II drug with poor solubility resulting in limited bioavailability. The present study aims at improving the so...

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Detalles Bibliográficos
Autores principales: Deshkar, Sanjeevani Shekhar, Borde, Govind R., Kale, Rupali N., Waghmare, Balasaheb A., Thomas, Asha Biju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903020/
https://www.ncbi.nlm.nih.gov/pubmed/29692975
http://dx.doi.org/10.4103/jphi.JPHI_39_17