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Adult Coats Disease Presenting as Subfoveal Nodule

A 21-year-old female presented with decreased vision in the right eye. Best corrected visual acuity was 6/60 in the right eye and 6/6 in the left eye. Funduscopy of the right eye revealed a subfoveal nodule with surrounding exudates and temporal peripheral retinal vessel telangiectasia with exudatio...

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Detalles Bibliográficos
Autores principales: Asaad, Salim Z., Hussain, Nazimul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903145/
https://www.ncbi.nlm.nih.gov/pubmed/29681842
http://dx.doi.org/10.1159/000487707
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author Asaad, Salim Z.
Hussain, Nazimul
author_facet Asaad, Salim Z.
Hussain, Nazimul
author_sort Asaad, Salim Z.
collection PubMed
description A 21-year-old female presented with decreased vision in the right eye. Best corrected visual acuity was 6/60 in the right eye and 6/6 in the left eye. Funduscopy of the right eye revealed a subfoveal nodule with surrounding exudates and temporal peripheral retinal vessel telangiectasia with exudation. The patient underwent retinal laser in the areas of telangiectatic vessels and capillary non-perfusion as seen on fundus fluorescein angiography. It was combined with an intravitreal injection of bevacizumab which was repeated twice at monthly intervals. The macular lesion and peripheral vessels along with subretinal exudates showed resolution during the course of treatment. However, the patient was lost to follow-up and returned 5 months later when examination revealed increased macular fibrosis. In the literature, the reported presentation of subfoveal nodule in Coats disease is during the first decade. It progresses to macular fibrosis within a few months. This case illustrates that subfoveal nodule before macular fibrosis in Coats disease may present later, even up to the third decade.
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spelling pubmed-59031452018-04-20 Adult Coats Disease Presenting as Subfoveal Nodule Asaad, Salim Z. Hussain, Nazimul Case Rep Ophthalmol Case Report A 21-year-old female presented with decreased vision in the right eye. Best corrected visual acuity was 6/60 in the right eye and 6/6 in the left eye. Funduscopy of the right eye revealed a subfoveal nodule with surrounding exudates and temporal peripheral retinal vessel telangiectasia with exudation. The patient underwent retinal laser in the areas of telangiectatic vessels and capillary non-perfusion as seen on fundus fluorescein angiography. It was combined with an intravitreal injection of bevacizumab which was repeated twice at monthly intervals. The macular lesion and peripheral vessels along with subretinal exudates showed resolution during the course of treatment. However, the patient was lost to follow-up and returned 5 months later when examination revealed increased macular fibrosis. In the literature, the reported presentation of subfoveal nodule in Coats disease is during the first decade. It progresses to macular fibrosis within a few months. This case illustrates that subfoveal nodule before macular fibrosis in Coats disease may present later, even up to the third decade. S. Karger AG 2018-03-22 /pmc/articles/PMC5903145/ /pubmed/29681842 http://dx.doi.org/10.1159/000487707 Text en Copyright © 2018 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Asaad, Salim Z.
Hussain, Nazimul
Adult Coats Disease Presenting as Subfoveal Nodule
title Adult Coats Disease Presenting as Subfoveal Nodule
title_full Adult Coats Disease Presenting as Subfoveal Nodule
title_fullStr Adult Coats Disease Presenting as Subfoveal Nodule
title_full_unstemmed Adult Coats Disease Presenting as Subfoveal Nodule
title_short Adult Coats Disease Presenting as Subfoveal Nodule
title_sort adult coats disease presenting as subfoveal nodule
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903145/
https://www.ncbi.nlm.nih.gov/pubmed/29681842
http://dx.doi.org/10.1159/000487707
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