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Aerobic Training Prevents Heatstrokes in Calsequestrin-1 Knockout Mice by Reducing Oxidative Stress
Calsequestrin-1 knockout (CASQ1-null) mice suffer lethal episodes when exposed to strenuous exercise and environmental heat, crises known as exertional/environmental heatstroke (EHS). We previously demonstrated that administration of exogenous antioxidants (N-acetylcysteine and trolox) reduces CASQ1...
Autores principales: | Guarnier, Flávia Alessandra, Michelucci, Antonio, Serano, Matteo, Pietrangelo, Laura, Pecorai, Claudia, Boncompagni, Simona, Protasi, Feliciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903204/ https://www.ncbi.nlm.nih.gov/pubmed/29849896 http://dx.doi.org/10.1155/2018/4652480 |
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