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Topical administration of regorafenib eye drops: phase I dose‐escalation study in healthy volunteers

AIM: Regorafenib is a multikinase inhibitor under investigation for use in neovascular age‐related macular degeneration. In this phase I study, regorafenib eye drops were administered to healthy volunteers to provide information on safety, tolerability and systemic exposure. METHODS: This was a sing...

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Detalles Bibliográficos
Autores principales:	Zimmermann, Torsten, Höchel, Joachim, Becka, Michael, Boettger, Michael K., Rohde, Beate, Schug, Barbara, Kunert, Kathleen S., Donath, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Clinical Trials
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903260/ https://www.ncbi.nlm.nih.gov/pubmed/29315699 http://dx.doi.org/10.1111/bcp.13502

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