Cargando…
A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei
Recent advances in magnetic resonance imaging methods, including data acquisition, pre-processing and analysis, have benefited research on the contributions of subcortical brain nuclei to human cognition and behavior. At the same time, these developments have led to an increasing need for a high-res...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903366/ https://www.ncbi.nlm.nih.gov/pubmed/29664465 http://dx.doi.org/10.1038/sdata.2018.63 |
_version_ | 1783314932339572736 |
---|---|
author | Pauli, Wolfgang M. Nili, Amanda N. Tyszka, J. Michael |
author_facet | Pauli, Wolfgang M. Nili, Amanda N. Tyszka, J. Michael |
author_sort | Pauli, Wolfgang M. |
collection | PubMed |
description | Recent advances in magnetic resonance imaging methods, including data acquisition, pre-processing and analysis, have benefited research on the contributions of subcortical brain nuclei to human cognition and behavior. At the same time, these developments have led to an increasing need for a high-resolution probabilistic in vivo anatomical atlas of subcortical nuclei. In order to address this need, we constructed high spatial resolution, three-dimensional templates, using high-accuracy diffeomorphic registration of T(1)- and T(2)- weighted structural images from 168 typical adults between 22 and 35 years old. In these templates, many tissue boundaries are clearly visible, which would otherwise be impossible to delineate in data from individual studies. The resulting delineations of subcortical nuclei complement current histology-based atlases. We further created a companion library of software tools for atlas development, to offer an open and evolving resource for the creation of a crowd-sourced in vivo probabilistic anatomical atlas of the human brain. |
format | Online Article Text |
id | pubmed-5903366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-59033662018-05-01 A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei Pauli, Wolfgang M. Nili, Amanda N. Tyszka, J. Michael Sci Data Data Descriptor Recent advances in magnetic resonance imaging methods, including data acquisition, pre-processing and analysis, have benefited research on the contributions of subcortical brain nuclei to human cognition and behavior. At the same time, these developments have led to an increasing need for a high-resolution probabilistic in vivo anatomical atlas of subcortical nuclei. In order to address this need, we constructed high spatial resolution, three-dimensional templates, using high-accuracy diffeomorphic registration of T(1)- and T(2)- weighted structural images from 168 typical adults between 22 and 35 years old. In these templates, many tissue boundaries are clearly visible, which would otherwise be impossible to delineate in data from individual studies. The resulting delineations of subcortical nuclei complement current histology-based atlases. We further created a companion library of software tools for atlas development, to offer an open and evolving resource for the creation of a crowd-sourced in vivo probabilistic anatomical atlas of the human brain. Nature Publishing Group 2018-04-17 /pmc/articles/PMC5903366/ /pubmed/29664465 http://dx.doi.org/10.1038/sdata.2018.63 Text en Copyright © 2018, The Author(s) http://creativecommons.org/licenses/by/4.0/ Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files made available in this article. |
spellingShingle | Data Descriptor Pauli, Wolfgang M. Nili, Amanda N. Tyszka, J. Michael A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei |
title | A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei |
title_full | A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei |
title_fullStr | A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei |
title_full_unstemmed | A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei |
title_short | A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei |
title_sort | high-resolution probabilistic in vivo atlas of human subcortical brain nuclei |
topic | Data Descriptor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903366/ https://www.ncbi.nlm.nih.gov/pubmed/29664465 http://dx.doi.org/10.1038/sdata.2018.63 |
work_keys_str_mv | AT pauliwolfgangm ahighresolutionprobabilisticinvivoatlasofhumansubcorticalbrainnuclei AT niliamandan ahighresolutionprobabilisticinvivoatlasofhumansubcorticalbrainnuclei AT tyszkajmichael ahighresolutionprobabilisticinvivoatlasofhumansubcorticalbrainnuclei AT pauliwolfgangm highresolutionprobabilisticinvivoatlasofhumansubcorticalbrainnuclei AT niliamandan highresolutionprobabilisticinvivoatlasofhumansubcorticalbrainnuclei AT tyszkajmichael highresolutionprobabilisticinvivoatlasofhumansubcorticalbrainnuclei |