Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects

INTRODUCTION: The development of novel analgesics to treat acute or chronic pain has been a challenge due to a lack of translatable measurements. Preclinical end points with improved translatability are necessary to more accurately inform clinical testing paradigms, which may help guide selection of...

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Detalles Bibliográficos
Autores principales: Vardigan, Joshua D, Houghton, Andrea K, Lange, Henry S, Adarayan, Emily D, Pall, Parul S, Ballard, Jeanine E, Henze, Darrell A, Uslaner, Jason M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903490/
https://www.ncbi.nlm.nih.gov/pubmed/29692626
http://dx.doi.org/10.2147/JPR.S152879

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