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Relationship Between INPP5E Gene Expression and Embryonic Neural Development in a Mouse Model of Neural Tube Defect

BACKGROUND: The INPP5E gene encodes for the inositol polyphosphate-5-phosphatase (INPP5E) 72 kDa protein that regulates the phosphoinositide signaling pathway and other cellular activities, but the functional role of this gene in embryonic neurodevelopment and neural tube defect (NTD) remains unclea...

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Detalles Bibliográficos
Autores principales: Yue, Huixuan, Zhu, Xiting, Li, Shen, Wang, Fang, Wang, Xiuwei, Guan, Zhen, Zhu, Zhiqiang, Niu, Bo, Zhang, Ting, Guo, Jin, Wang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903545/
https://www.ncbi.nlm.nih.gov/pubmed/29626185
http://dx.doi.org/10.12659/MSM.906095