Cost-benefit analysis of introducing next-generation sequencing (metagenomic) pathogen testing in the setting of pyrexia of unknown origin

Pyrexia of unknown origin (PUO) is defined as a temperature of >38.3°C that lasts for >3 weeks, where no cause can be found despite appropriate investigation. Existing protocols for the work-up of PUO can be extensive and costly, motivating the application of recent advances in molecular diagn...

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Detalles Bibliográficos
Autores principales: Chai, Jia Hui, Lee, Chun Kiat, Lee, Hong Kai, Wong, Nicholas, Teo, Kahwee, Tan, Chuen Seng, Thokala, Praveen, Tang, Julian Wei-Tze, Tambyah, Paul Anantharajah, Oh, Vernon Min Sen, Loh, Tze Ping, Yoong, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903630/
https://www.ncbi.nlm.nih.gov/pubmed/29664913
http://dx.doi.org/10.1371/journal.pone.0194648

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