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Silencing of peroxiredoxin II by promoter methylation is necessary for the survival and migration of gastric cancer cells

Peroxiredoxin (Prx), a family of ubiquitous thiol peroxidases, functions as a redox signaling regulator that controls cellular H(2)O(2) in mammalian cells and has recently received attention for being overexpressed in various cancer types. In this study, we show that Prx type II (PrxII) is rather si...

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Detalles Bibliográficos
Autores principales: Hong, Soo Hyun, Min, Chengchun, Jun, Yukyung, Lee, Doo Jae, Kim, Seung Hwa, Park, Joo Hyun, Cheong, Jae Ho, Park, Yoon Jung, Kim, Soo-Youl, Lee, Sanghyuk, Kang, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903821/
https://www.ncbi.nlm.nih.gov/pubmed/29422545
http://dx.doi.org/10.1038/emm.2017.267