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Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β

BACKGROUND & AIMS: The organic solute transporter α-β (OSTα-OSTβ) mainly facilitates transport of bile acids across the basolateral membrane of ileal enterocytes. Therefore, inhibition of OSTα-OSTβ might have similar beneficial metabolic effects as intestine-specific agonists of the major nuclea...

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Detalles Bibliográficos
Autores principales:	van de Wiel, Sandra M.W., de Waart, D. Rudi, Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904037/ https://www.ncbi.nlm.nih.gov/pubmed/29675448 http://dx.doi.org/10.1016/j.jcmgh.2017.11.011

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