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Cftr Modulates Wnt/β-Catenin Signaling and Stem Cell Proliferation in Murine Intestine
BACKGROUND & AIMS: Cystic fibrosis (CF) patients and CF mouse models have increased risk for gastrointestinal tumors. CF mice show augmented intestinal proliferation of unknown etiology and an altered intestinal environment. We examined the role of the cystic fibrosis transmembrane conductance r...
Autores principales: | Strubberg, Ashlee M., Liu, Jinghua, Walker, Nancy M., Stefanski, Casey D., MacLeod, R. John, Magness, Scott T., Clarke, Lane L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904038/ https://www.ncbi.nlm.nih.gov/pubmed/29675451 http://dx.doi.org/10.1016/j.jcmgh.2017.11.013 |
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