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Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism
BACKGROUND & AIMS: Alcohol-induced progression of hepatitis C virus (HCV) infection is related to dysfunction of innate immunity in hepatocytes. Endogenously produced interferon (IFN)α induces activation of interferon-stimulated genes (ISGs) via triggering of the Janus kinase–signal transducer a...
Autores principales: | Ganesan, Murali, Tikhanovich, Irina, Vangimalla, Shiva Shankar, Dagur, Raghubendra Singh, Wang, Weimin, Poluektova, Larisa I., Sun, Yimin, Mercer, David F., Tuma, Dean, Weinman, Steven A., Kharbanda, Kusum K., Osna, Natalia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904050/ https://www.ncbi.nlm.nih.gov/pubmed/29693039 http://dx.doi.org/10.1016/j.jcmgh.2017.10.004 |
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