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Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients

Mutations in KRAS exon 2, BRAF and PIK3CA are commonly present in colorectal cancer (CRC) worldwide, but few data about RAS mutations outside KRAS exon 2 are available for Chinese CRCs. We, therefore, determined the mutation frequencies and prognostic values of KRAS exon 2, 3 and 4, NRAS exon 2 and...

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Detalles Bibliográficos
Autores principales:	Guo, Fang, Gong, Hai, Zhao, Huanhuan, Chen, Jing, Zhang, Yiming, Zhang, Lihua, Shi, Xin, Zhang, Aifeng, Jin, Hui, Zhang, Jianqiong, He, Youji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904111/ https://www.ncbi.nlm.nih.gov/pubmed/29666387 http://dx.doi.org/10.1038/s41598-018-24306-1

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