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Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes

L-ascorbic acid (Vitamin C) can enhance the meiotic maturation and developmental competence of porcine oocytes, but the underlying molecular mechanism remains obscure. Here we show the role of ascorbic acid in regulating epigenetic status of both nucleic acids and chromatin to promote oocyte maturat...

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Detalles Bibliográficos
Autores principales:	Yu, Xiao-Xia, Liu, Yun-Hua, Liu, Xiao-Man, Wang, Pei-Chao, Liu, Shuai, Miao, Jia-Kun, Du, Zhi-Qiang, Yang, Cai-Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904140/ https://www.ncbi.nlm.nih.gov/pubmed/29666467 http://dx.doi.org/10.1038/s41598-018-24395-y

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