Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression

Knowledge of stromal factors that have a role in the transcriptional regulation of metabolic pathways aside from c-Myc is fundamental to improvements in lymphoma therapy. Using a MYC-inducible human B-cell line, we observed the cooperative activation of STAT3 and NF-κB by IL10 and CpG stimulation. W...

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Detalles Bibliográficos
Autores principales: Feist, Maren, Schwarzfischer, Philipp, Heinrich, Paul, Sun, Xueni, Kemper, Judith, von Bonin, Frederike, Perez-Rubio, Paula, Taruttis, Franziska, Rehberg, Thorsten, Dettmer, Katja, Gronwald, Wolfram, Reinders, Jörg, Engelmann, Julia C., Dudek, Jan, Klapper, Wolfram, Trümper, Lorenz, Spang, Rainer, Oefner, Peter J., Kube, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904148/
https://www.ncbi.nlm.nih.gov/pubmed/29666362
http://dx.doi.org/10.1038/s41467-018-03803-x

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