Cargando…

Influence of APOA5 Locus on the Treatment Efficacy of Three Statins: Evidence From a Randomized Pilot Study in Chinese Subjects

Pharmacogenetics or pharmacogenomics approaches are important for addressing the individual variabilities of drug efficacy especially in the era of precision medicine. One particular interesting gene to investigate is APOA5, which has been repeatedly linked with the inter-individual variations of se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hua, Sha, Ma, Chuanxiang, Zhang, Jun, Li, Jing, Wu, Weiwei, Xu, Ning, Luo, Guanghua, Zhao, Jianrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904201/ https://www.ncbi.nlm.nih.gov/pubmed/29695967 http://dx.doi.org/10.3389/fphar.2018.00352

Ejemplares similares

HDL/ApoA-1 infusion and ApoA-1 gene therapy in atherosclerosis
por: Chyu, Kuang-Yuh, et al.
Publicado: (2015)

Targeting the Apoa1 locus for liver-directed gene therapy
por: De Giorgi, Marco, et al.
Publicado: (2021)

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction
por: Trompet, Stella, et al.
Publicado: (2022)

National Background is Associated with Disparities in Initiation and Persistence to Statin Treatment in Subjects with Diabetes in Denmark
por: Dominguez, Helena, et al.
Publicado: (2010)

Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine
por: Huang, Piao-Piao, et al.
Publicado: (2022)

Risk of Myopathy in Patients in Therapy with Statins: Identification of Biological Markers in a Pilot Study
por: Camerino, Giulia M., et al.
Publicado: (2017)

Traditional Chinese Medicine Intervenes Ventricular Remodeling Following Acute Myocardial Infarction: Evidence From 40 Random Controlled Trials With 3,659 Subjects
por: Zhang, Xiao-Xiao, et al.
Publicado: (2021)

Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects
por: Domínguez-Reyes, Teresa, et al.
Publicado: (2015)

Impact of Plasma Exposure of Statins and Their Metabolites With Major Adverse Cardiovascular Events in Chinese Patients With Coronary Artery Disease
por: Zhou, Xiao-hong, et al.
Publicado: (2020)

A long non-coding RNA, APOA4-AS, regulates APOA4 expression depending on HuR in mice
por: Qin, Wangshu, et al.
Publicado: (2016)

High Plasma Exposure of Statins Associated With Increased Risk of Contrast-Induced Acute Kidney Injury in Chinese Patients With Coronary Artery Disease
por: Cai, Liyun, et al.
Publicado: (2018)

Composition, Clinical Efficiency, and Mechanism of NHC-Approved “Three Chinese Medicines and Three Chinese Recipes” for COVID-19 Treatment
por: Xia, Ke-Yao, et al.
Publicado: (2022)

Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome
por: Wu, Yanhua, et al.
Publicado: (2016)

New insights into the therapeutic potentials of statins in cancer
por: Liu, Chengyu, et al.
Publicado: (2023)

A Chinese Medicine Formula (Bushen Huoxue Tongluo) for the Treatment of Chronic Subjective Tinnitus: A Study Protocol for a Pilot, Assessor-Blinded, Randomized Clinical Trial
por: Zhang, Hong Wei, et al.
Publicado: (2022)

Pharmacokinetics, Safety and Pharmacokinetics/Pharmacodynamics Analysis of Omadacycline in Chinese Healthy Subjects
por: Yang, Haijing, et al.
Publicado: (2022)

Association of rs662799 in APOA5 with CAD in Chinese Han population
por: Chen, Hua, et al.
Publicado: (2018)

Efficacy of Chinese Herbal Formula Sini Zuojin Decoction in Treating Gastroesophageal Reflux Disease: Clinical Evidence and Potential Mechanisms
por: Li, Shaowei, et al.
Publicado: (2020)

Efficacy and Safety of Leflunomide for Refractory COVID-19: A Pilot Study
por: Wang, Qiang, et al.
Publicado: (2021)

Corrigendum: A Chinese medicine formula (Bushen Huoxue Tongluo) for the treatment of chronic subjective tinnitus: a study protocol for a pilot, assessor-blinded, randomized clinical trial
por: Zhang, Hong Wei, et al.
Publicado: (2023)

Relationship between Statin Utilization and Socioeconomic Deprivation in Hungary
por: Boruzs, Klára, et al.
Publicado: (2016)

The Role of Statins in Prevention of Preeclampsia: A Promise for the Future?
por: Katsi, Vasiliki, et al.
Publicado: (2017)

The Efficacy and Safety of a Fixed Combination of Chinese Herbal Medicine in Chronic Urticaria: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
por: Yang, Sien-Hung, et al.
Publicado: (2018)

Efficacy and safety of Chinese herbal medicine for pneumonia convalescence in children: A systematic review and meta-analysis
por: Guo, Jian-Ning, et al.
Publicado: (2022)

Effects of Tenofovir on the Single-Dose Pharmacokinetics of Intravenous Morinidazole in Healthy Chinese Subjects
por: Wu, Guolan, et al.
Publicado: (2020)

An ApoA-I Mimic Peptide of 4F Promotes SDF-1α Expression in Endothelial Cells Through PI3K/Akt/ERK/HIF-1α Signaling Pathway
por: Lv, Kaixuan, et al.
Publicado: (2022)

TRPV1: A promising therapeutic target for skin aging and inflammatory skin diseases
por: Xiao, Tengfei, et al.
Publicado: (2023)

Efficacy and safety of Chinese herbal medicine for atopic dermatitis: Evidence from eight high-quality randomized placebo-controlled trials
por: Cai, Xiaoce, et al.
Publicado: (2022)

Effects of Non-statin Lipid-Modifying Agents on Cardiovascular Morbidity and Mortality Among Statin-Treated Patients: A Systematic Review and Network Meta-Analysis
por: Chaiyasothi, Thanaputt, et al.
Publicado: (2019)

A Biosimilarity Study Between QX001S and Ustekinumab in Healthy Chinese Male Subjects
por: Gao, Lei, et al.
Publicado: (2021)

Tolerability, Safety, Pharmacokinetics and Drug Interaction of Cefotaxime Sodium–Tazobactam Sodium Injection (6:1) Following Single and Multiple Intravenous Doses in Chinese Healthy Subjects
por: Chen, Ning, et al.
Publicado: (2020)

Impact of Gastric H(+)/K(+)-ATPase rs2733743 on the Intragastric pH-Values of Dexlansoprazole Injection in Chinese Subjects
por: Sun, Lu-Ning, et al.
Publicado: (2017)

Traditional Chinese Medicine for Bradyarrhythmia: Evidence and Potential Mechanisms
por: Liu, Shuo, et al.
Publicado: (2018)

Efficacy and safety of traditional Chinese medicine adjuvant therapy for severe pneumonia: evidence mapping of the randomized controlled trials, systematic reviews, and meta-analyses
por: Xie, Kai, et al.
Publicado: (2023)

Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure
por: Wang, Anzhu, et al.
Publicado: (2022)

The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins
por: Mo, Huanbiao, et al.
Publicado: (2019)

Statins as Adjuvant Therapy for COVID-19 to Calm the Stormy Immunothrombosis and Beyond
por: Vuorio, Alpo, et al.
Publicado: (2021)

Statins for the Treatment of Pulmonary Hypertension in Patients with Chronic Obstructive Pulmonary Disease
por: Chen, Chung-Yu, et al.
Publicado: (2021)

Patterns of statin adherence in primary cardiovascular disease prevention during the pandemic
por: Malo, Sara, et al.
Publicado: (2022)

Pharmacokinetics and safety of the two oral cefaclor formulations in healthy chinese subjects in the fasting and postprandial states
por: Qu, Xinyao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u3imhasghj8k73cbko8anps1v0