Cargando…

Tissue-specific transcriptome profiling of Drosophila reveals roles for GATA transcription factors in longevity by dietary restriction

Dietary restriction (DR) extends animal lifespan, but imposes fitness costs. This phenomenon depends on dietary essential amino acids (EAAs) and TOR signalling, which exert systemic effects. However, the roles of specific tissues and cell-autonomous transcriptional regulators in diverse aspects of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dobson, Adam J., He, Xiaoli, Blanc, Eric, Bolukbasi, Ekin, Feseha, Yodit, Yang, Mingyao, Piper, Matthew D. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904217/
https://www.ncbi.nlm.nih.gov/pubmed/29675265
http://dx.doi.org/10.1038/s41514-018-0024-4