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Evidence-Based Design of Fixed-Dose Combinations: Principles and Application to Pediatric Anti-Tuberculosis Therapy

BACKGROUND AND OBJECTIVES: Fixed-dose combination formulations where several drugs are included in one tablet are important for the implementation of many long-term multidrug therapies. The selection of optimal dose ratios and tablet content of a fixed-dose combination and the design of individualiz...

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Detalles Bibliográficos
Autores principales: Svensson, Elin M., Yngman, Gunnar, Denti, Paolo, McIlleron, Helen, Kjellsson, Maria C., Karlsson, Mats O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904239/
https://www.ncbi.nlm.nih.gov/pubmed/28779464
http://dx.doi.org/10.1007/s40262-017-0577-6