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Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records
Bipolar disorder (BD) is a heritable mood disorder characterized by episodes of mania and depression. Although genomewide association studies (GWAS) have successfully identified genetic loci contributing to BD risk, sample size has become a rate-limiting obstacle to genetic discovery. Electronic hea...
Autores principales: | Chen, Chia-Yen, Lee, Phil H., Castro, Victor M., Minnier, Jessica, Charney, Alexander W., Stahl, Eli A., Ruderfer, Douglas M., Murphy, Shawn N., Gainer, Vivian, Cai, Tianxi, Jones, Ian, Pato, Carlos N., Pato, Michele T., Landén, Mikael, Sklar, Pamela, Perlis, Roy H., Smoller, Jordan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904248/ https://www.ncbi.nlm.nih.gov/pubmed/29666432 http://dx.doi.org/10.1038/s41398-018-0133-7 |
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