Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

Brain-derived neurotrophic factor (BDNF) plays important functions in cell survival and differentiation, neuronal outgrowth and plasticity. In Alzheimer’s disease (AD), BDNF signaling is known to be impaired, partially because amyloid β (Aβ) induces truncation of BDNF main receptor, TrkB-full length...

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Detalles Bibliográficos
Autores principales: Tanqueiro, Sara R., Ramalho, Rita M., Rodrigues, Tiago M., Lopes, Luísa V., Sebastião, Ana M., Diógenes, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904251/
https://www.ncbi.nlm.nih.gov/pubmed/29695962
http://dx.doi.org/10.3389/fphar.2018.00237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904251/
https://www.ncbi.nlm.nih.gov/pubmed/29695962
http://dx.doi.org/10.3389/fphar.2018.00237

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