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Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

Brain-derived neurotrophic factor (BDNF) plays important functions in cell survival and differentiation, neuronal outgrowth and plasticity. In Alzheimer’s disease (AD), BDNF signaling is known to be impaired, partially because amyloid β (Aβ) induces truncation of BDNF main receptor, TrkB-full length...

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Detalles Bibliográficos
Autores principales:	Tanqueiro, Sara R., Ramalho, Rita M., Rodrigues, Tiago M., Lopes, Luísa V., Sebastião, Ana M., Diógenes, Maria J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904251/ https://www.ncbi.nlm.nih.gov/pubmed/29695962 http://dx.doi.org/10.3389/fphar.2018.00237

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