A Glimpse Into the Structure and Function of Atypical Type I Chaperonins

Chaperonins are a subclass of molecular chaperones that assist cellular proteins to fold and assemble into their native shape. Much work has been done on Type I chaperonins, which has elucidated their elegant mechanism. Some debate remains about the details in these mechanisms, but nonetheless the r...

Descripción completa

Detalles Bibliográficos
Autores principales: Ansari, Mohammed Y., Mande, Shekhar C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904260/
https://www.ncbi.nlm.nih.gov/pubmed/29696145
http://dx.doi.org/10.3389/fmolb.2018.00031
_version_ 1783315067899478016
author Ansari, Mohammed Y.
Mande, Shekhar C.
author_facet Ansari, Mohammed Y.
Mande, Shekhar C.
author_sort Ansari, Mohammed Y.
collection PubMed
description Chaperonins are a subclass of molecular chaperones that assist cellular proteins to fold and assemble into their native shape. Much work has been done on Type I chaperonins, which has elucidated their elegant mechanism. Some debate remains about the details in these mechanisms, but nonetheless the roles of these in helping protein folding have been understood in great depth. In this review we discuss the known functions of atypical Type I chaperonins, highlighting evolutionary aspects that might lead chaperonins to perform alternate functions.
format Online
Article
Text
id pubmed-5904260
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-59042602018-04-25 A Glimpse Into the Structure and Function of Atypical Type I Chaperonins Ansari, Mohammed Y. Mande, Shekhar C. Front Mol Biosci Molecular Biosciences Chaperonins are a subclass of molecular chaperones that assist cellular proteins to fold and assemble into their native shape. Much work has been done on Type I chaperonins, which has elucidated their elegant mechanism. Some debate remains about the details in these mechanisms, but nonetheless the roles of these in helping protein folding have been understood in great depth. In this review we discuss the known functions of atypical Type I chaperonins, highlighting evolutionary aspects that might lead chaperonins to perform alternate functions. Frontiers Media S.A. 2018-04-11 /pmc/articles/PMC5904260/ /pubmed/29696145 http://dx.doi.org/10.3389/fmolb.2018.00031 Text en Copyright © 2018 Ansari and Mande. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Molecular Biosciences
Ansari, Mohammed Y.
Mande, Shekhar C.
A Glimpse Into the Structure and Function of Atypical Type I Chaperonins
title A Glimpse Into the Structure and Function of Atypical Type I Chaperonins
title_full A Glimpse Into the Structure and Function of Atypical Type I Chaperonins
title_fullStr A Glimpse Into the Structure and Function of Atypical Type I Chaperonins
title_full_unstemmed A Glimpse Into the Structure and Function of Atypical Type I Chaperonins
title_short A Glimpse Into the Structure and Function of Atypical Type I Chaperonins
title_sort glimpse into the structure and function of atypical type i chaperonins
topic Molecular Biosciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904260/
https://www.ncbi.nlm.nih.gov/pubmed/29696145
http://dx.doi.org/10.3389/fmolb.2018.00031
work_keys_str_mv AT ansarimohammedy aglimpseintothestructureandfunctionofatypicaltypeichaperonins
AT mandeshekharc aglimpseintothestructureandfunctionofatypicaltypeichaperonins
AT ansarimohammedy glimpseintothestructureandfunctionofatypicaltypeichaperonins
AT mandeshekharc glimpseintothestructureandfunctionofatypicaltypeichaperonins

Ejemplares similares