Genetic Polymorphism at CCL5 Is Associated With Protection in Chagas’ Heart Disease: Antagonistic Participation of CCR1(+) and CCR5(+) Cells in Chronic Chagasic Cardiomyopathy

Chronic cardiomyopathy is the main clinical manifestation of Chagas disease (CD), a disease caused by Trypanosoma cruzi infection. A hallmark of chronic chagasic cardiomyopathy (CCC) is a fibrogenic inflammation mainly composed of CD8(+) and CD4(+) T cells and macrophages. CC-chemokine ligands and r...

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Detalles Bibliográficos
Autores principales: Batista, Angelica Martins, Alvarado-Arnez, Lucia Elena, Alves, Silvia Marinho, Melo, Gloria, Pereira, Isabela Resende, Ruivo, Leonardo Alexandre de Souza, da Silva, Andrea Alice, Gibaldi, Daniel, da Silva, Thayse do E. S. Protásio, de Lorena, Virginia Maria Barros, de Melo, Adriene Siqueira, de Araújo Soares, Ana Karine, Barros, Michelle da Silva, Costa, Vláudia Maria Assis, Cardoso, Cynthia C., Pacheco, Antonio G., Carrazzone, Cristina, Oliveira, Wilson, Moraes, Milton Ozório, Lannes-Vieira, Joseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904358/
https://www.ncbi.nlm.nih.gov/pubmed/29696014
http://dx.doi.org/10.3389/fimmu.2018.00615

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