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Endoscopic Vacuum-Assisted Closure Therapy in Patients with Anastomotic Leakage after Esophagectomy: A Single-Center Experience
AIM: To study the efficacy of E-VAC therapy for patients with anastomotic leakage after esophagectomy. METHODS: Between January 2013 and April 2017, 12 patients underwent E-VAC therapy for the management of postoperative leakage. Their clinical features and endoscopic procedure details, therapy resu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904779/ https://www.ncbi.nlm.nih.gov/pubmed/29849581 http://dx.doi.org/10.1155/2018/1697968 |
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author | Noh, Soo Min Ahn, Ji Yong Lee, Jeong Hoon Jung, Hwoon-Yong AlGhamdi, Zeead Kim, Hyeong Ryul Kim, Yong-Hee |
author_facet | Noh, Soo Min Ahn, Ji Yong Lee, Jeong Hoon Jung, Hwoon-Yong AlGhamdi, Zeead Kim, Hyeong Ryul Kim, Yong-Hee |
author_sort | Noh, Soo Min |
collection | PubMed |
description | AIM: To study the efficacy of E-VAC therapy for patients with anastomotic leakage after esophagectomy. METHODS: Between January 2013 and April 2017, 12 patients underwent E-VAC therapy for the management of postoperative leakage. Their clinical features and endoscopic procedure details, therapy results, adverse events, and survival were investigated. RESULTS: All 12 patients were male and the median age was 57 years (interquartile range 51.5–62.8 years). The reasons for esophageal surgery were esophageal cancer (83.3%), gastrointestinal stromal tumor (8.3%), and esophageal diverticulum (8.3%). Prior to E-VAC therapy, 6 patients had undergone failed primary surgical repair and the median duration from esophagectomy to leakage discovery was 13.5 days (IQR 6–207 days). The median duration of E-VAC therapy was 25 days (IQR 13.5–34.8 days) and the average sponge exchange rate was 2.7 times during the treatment period. After E-VAC therapy, 8 patients (66.7%) had complete leakage closure, 3 (25%) had a decreased leakage size, and 1 (8.3%) was unchanged. The three patients with a decreased leakage size after E-VAC therapy were treated with endoscopic and conservative management without further surgery. CONCLUSION: With proper patient selection, E-VAC therapy is a feasible and safe method for the treatment of anastomotic leakage after esophagectomy. |
format | Online Article Text |
id | pubmed-5904779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-59047792018-05-30 Endoscopic Vacuum-Assisted Closure Therapy in Patients with Anastomotic Leakage after Esophagectomy: A Single-Center Experience Noh, Soo Min Ahn, Ji Yong Lee, Jeong Hoon Jung, Hwoon-Yong AlGhamdi, Zeead Kim, Hyeong Ryul Kim, Yong-Hee Gastroenterol Res Pract Research Article AIM: To study the efficacy of E-VAC therapy for patients with anastomotic leakage after esophagectomy. METHODS: Between January 2013 and April 2017, 12 patients underwent E-VAC therapy for the management of postoperative leakage. Their clinical features and endoscopic procedure details, therapy results, adverse events, and survival were investigated. RESULTS: All 12 patients were male and the median age was 57 years (interquartile range 51.5–62.8 years). The reasons for esophageal surgery were esophageal cancer (83.3%), gastrointestinal stromal tumor (8.3%), and esophageal diverticulum (8.3%). Prior to E-VAC therapy, 6 patients had undergone failed primary surgical repair and the median duration from esophagectomy to leakage discovery was 13.5 days (IQR 6–207 days). The median duration of E-VAC therapy was 25 days (IQR 13.5–34.8 days) and the average sponge exchange rate was 2.7 times during the treatment period. After E-VAC therapy, 8 patients (66.7%) had complete leakage closure, 3 (25%) had a decreased leakage size, and 1 (8.3%) was unchanged. The three patients with a decreased leakage size after E-VAC therapy were treated with endoscopic and conservative management without further surgery. CONCLUSION: With proper patient selection, E-VAC therapy is a feasible and safe method for the treatment of anastomotic leakage after esophagectomy. Hindawi 2018-04-04 /pmc/articles/PMC5904779/ /pubmed/29849581 http://dx.doi.org/10.1155/2018/1697968 Text en Copyright © 2018 Soo Min Noh et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Noh, Soo Min Ahn, Ji Yong Lee, Jeong Hoon Jung, Hwoon-Yong AlGhamdi, Zeead Kim, Hyeong Ryul Kim, Yong-Hee Endoscopic Vacuum-Assisted Closure Therapy in Patients with Anastomotic Leakage after Esophagectomy: A Single-Center Experience |
title | Endoscopic Vacuum-Assisted Closure Therapy in Patients with Anastomotic Leakage after Esophagectomy: A Single-Center Experience |
title_full | Endoscopic Vacuum-Assisted Closure Therapy in Patients with Anastomotic Leakage after Esophagectomy: A Single-Center Experience |
title_fullStr | Endoscopic Vacuum-Assisted Closure Therapy in Patients with Anastomotic Leakage after Esophagectomy: A Single-Center Experience |
title_full_unstemmed | Endoscopic Vacuum-Assisted Closure Therapy in Patients with Anastomotic Leakage after Esophagectomy: A Single-Center Experience |
title_short | Endoscopic Vacuum-Assisted Closure Therapy in Patients with Anastomotic Leakage after Esophagectomy: A Single-Center Experience |
title_sort | endoscopic vacuum-assisted closure therapy in patients with anastomotic leakage after esophagectomy: a single-center experience |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904779/ https://www.ncbi.nlm.nih.gov/pubmed/29849581 http://dx.doi.org/10.1155/2018/1697968 |
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