Glycine Protects H9C2 Cardiomyocytes from High Glucose- and Hypoxia/Reoxygenation-Induced Injury via Inhibiting PKCβ2 Activation and Improving Mitochondrial Quality

BACKGROUND: Patients with diabetes are more vulnerable to myocardial ischemia reperfusion injury (IRI), which is involved in PKCβ2 activation and mitochondrial dysfunction. Glycine has been documented as a cytoprotective agent to attenuate diabetes-related abnormalities and reduce myocardial IRI, bu...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Su, Wating, Zhang, Qiongxia, Xu, Jinjin, Liu, Huimin, Luo, Jun, Zhan, Liying, Xia, Zhongyuan, Lei, Shaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904807/
https://www.ncbi.nlm.nih.gov/pubmed/29850613
http://dx.doi.org/10.1155/2018/9502895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904807/
https://www.ncbi.nlm.nih.gov/pubmed/29850613
http://dx.doi.org/10.1155/2018/9502895

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