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Glycine Protects H9C2 Cardiomyocytes from High Glucose- and Hypoxia/Reoxygenation-Induced Injury via Inhibiting PKCβ2 Activation and Improving Mitochondrial Quality
BACKGROUND: Patients with diabetes are more vulnerable to myocardial ischemia reperfusion injury (IRI), which is involved in PKCβ2 activation and mitochondrial dysfunction. Glycine has been documented as a cytoprotective agent to attenuate diabetes-related abnormalities and reduce myocardial IRI, bu...
Autores principales: | Zhang, Yuan, Su, Wating, Zhang, Qiongxia, Xu, Jinjin, Liu, Huimin, Luo, Jun, Zhan, Liying, Xia, Zhongyuan, Lei, Shaoqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904807/ https://www.ncbi.nlm.nih.gov/pubmed/29850613 http://dx.doi.org/10.1155/2018/9502895 |
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