Apelin-13 Is an Early Promoter of Cytoskeleton and Tight Junction in Diabetic Macular Edema via PI-3K/Akt and MAPK/Erk Signaling Pathways

Diabetic macular edema is major cause of vision loss associated with diabetic retinopathy. Breakdown of blood-retinal barrier, especially inner BRB, is an early event in pathogenesis of DR. Apelin, an endogenous ligand of APJ, mediates angiogenesis and is involved in the development of DR. The prese...

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Detalles Bibliográficos
Autores principales: Li, Yang, Bai, Yu-jing, Jiang, Yan-rong, Yu, Wen-zhen, Shi, Xuan, Chen, Li, Feng, Jing, Sun, Gui-bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904819/
https://www.ncbi.nlm.nih.gov/pubmed/29850504
http://dx.doi.org/10.1155/2018/3242574

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