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Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment

BACKGROUND: Elderly patients are more likely to suffer from postoperative cognitive dysfunction (POCD) after surgery and anesthesia. Except for declined organ function, the particular pathogenesis of POCD in elderly patients remains unknown. This study is carried out to determine the critical role o...

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Detalles Bibliográficos
Autores principales:	Wang, Zhi, Meng, Shiyu, Cao, Lin, Chen, Ying, Zuo, Zhiyi, Peng, Shuling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904978/ https://www.ncbi.nlm.nih.gov/pubmed/29665808 http://dx.doi.org/10.1186/s12974-018-1137-1

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