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Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study

BACKGROUND: Periprostatic adipose tissue (PPAT) has been recognized to associate with prostate cancer (PCa) aggressiveness and progression. Here, we sought to investigate whether excess adiposity modulates the methylome of PPAT in PCa patients. DNA methylation profiling was performed in PPAT from ob...

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Detalles Bibliográficos
Autores principales: Cheng, Yan, Monteiro, Cátia, Matos, Andreia, You, Jiaying, Fraga, Avelino, Pereira, Carina, Catalán, Victoria, Rodríguez, Amaia, Gómez-Ambrosi, Javier, Frühbeck, Gema, Ribeiro, Ricardo, Hu, Pingzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904983/
https://www.ncbi.nlm.nih.gov/pubmed/29692867
http://dx.doi.org/10.1186/s13148-018-0490-3

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