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Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study
BACKGROUND: Periprostatic adipose tissue (PPAT) has been recognized to associate with prostate cancer (PCa) aggressiveness and progression. Here, we sought to investigate whether excess adiposity modulates the methylome of PPAT in PCa patients. DNA methylation profiling was performed in PPAT from ob...
Autores principales: | Cheng, Yan, Monteiro, Cátia, Matos, Andreia, You, Jiaying, Fraga, Avelino, Pereira, Carina, Catalán, Victoria, Rodríguez, Amaia, Gómez-Ambrosi, Javier, Frühbeck, Gema, Ribeiro, Ricardo, Hu, Pingzhao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904983/ https://www.ncbi.nlm.nih.gov/pubmed/29692867 http://dx.doi.org/10.1186/s13148-018-0490-3 |
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