A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders

BACKGROUND: Mutations in the SHANK genes, which encode postsynaptic scaffolding proteins, have been linked to a spectrum of neurodevelopmental disorders. The SHANK genes and the schizophrenia-associated microRNA-137 show convergence on several levels, as they are both expressed at the synapse, influ...

Descripción completa

Detalles Bibliográficos
Autores principales: de Sena Cortabitarte, Ana, Berkel, Simone, Cristian, Flavia-Bianca, Fischer, Christine, Rappold, Gudrun A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905159/
https://www.ncbi.nlm.nih.gov/pubmed/29665782
http://dx.doi.org/10.1186/s11689-018-9233-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905159/
https://www.ncbi.nlm.nih.gov/pubmed/29665782
http://dx.doi.org/10.1186/s11689-018-9233-1

Ejemplares similares