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A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders
BACKGROUND: Mutations in the SHANK genes, which encode postsynaptic scaffolding proteins, have been linked to a spectrum of neurodevelopmental disorders. The SHANK genes and the schizophrenia-associated microRNA-137 show convergence on several levels, as they are both expressed at the synapse, influ...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905159/ https://www.ncbi.nlm.nih.gov/pubmed/29665782 http://dx.doi.org/10.1186/s11689-018-9233-1 |