Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions

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The case of a 64-year-old man with spontaneous acute abdominal bleeding is presented. Under suspicion of an atypical hepatocellular carcinoma an extended left hemihepatectomy was performed. Histological diagnosis after surgical therapy revealed a primary hepatic choriocarcinoma. During follow-up wit...

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Autores principales: Kohler, Alexander, Welsch, Thilo, Sturm, Anne-Kathrin, Baretton, Gustavo B, Reissfelder, Christoph, Weitz, Jürgen, Riediger, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905376/
https://www.ncbi.nlm.nih.gov/pubmed/29686836
http://dx.doi.org/10.1093/jscr/rjy068
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author Kohler, Alexander
Welsch, Thilo
Sturm, Anne-Kathrin
Baretton, Gustavo B
Reissfelder, Christoph
Weitz, Jürgen
Riediger, Carina
author_facet Kohler, Alexander
Welsch, Thilo
Sturm, Anne-Kathrin
Baretton, Gustavo B
Reissfelder, Christoph
Weitz, Jürgen
Riediger, Carina
author_sort Kohler, Alexander
collection PubMed
description The case of a 64-year-old man with spontaneous acute abdominal bleeding is presented. Under suspicion of an atypical hepatocellular carcinoma an extended left hemihepatectomy was performed. Histological diagnosis after surgical therapy revealed a primary hepatic choriocarcinoma. During follow-up within 5 months several metastases were detected. Because of the number and localization of the metastases, there was no further curative surgical option and palliative systemic chemotherapy was initiated. Primary choriocarcinoma of the liver is an important differential-diagnosis in hypervascularized lesions of the liver. This tumor-entity is highly aggressive, with rapid tendency for metastatic spreading. This correlates with the poor prognosis of 12 months after tumor-detection.
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spelling pubmed-59053762018-04-23 Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions Kohler, Alexander Welsch, Thilo Sturm, Anne-Kathrin Baretton, Gustavo B Reissfelder, Christoph Weitz, Jürgen Riediger, Carina J Surg Case Rep Case Report The case of a 64-year-old man with spontaneous acute abdominal bleeding is presented. Under suspicion of an atypical hepatocellular carcinoma an extended left hemihepatectomy was performed. Histological diagnosis after surgical therapy revealed a primary hepatic choriocarcinoma. During follow-up within 5 months several metastases were detected. Because of the number and localization of the metastases, there was no further curative surgical option and palliative systemic chemotherapy was initiated. Primary choriocarcinoma of the liver is an important differential-diagnosis in hypervascularized lesions of the liver. This tumor-entity is highly aggressive, with rapid tendency for metastatic spreading. This correlates with the poor prognosis of 12 months after tumor-detection. Oxford University Press 2018-04-12 /pmc/articles/PMC5905376/ /pubmed/29686836 http://dx.doi.org/10.1093/jscr/rjy068 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Kohler, Alexander
Welsch, Thilo
Sturm, Anne-Kathrin
Baretton, Gustavo B
Reissfelder, Christoph
Weitz, Jürgen
Riediger, Carina
Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions
title Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions
title_full Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions
title_fullStr Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions
title_full_unstemmed Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions
title_short Primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions
title_sort primary choriocarcinoma of the liver: a rare, but important differential diagnosis of liver lesions
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905376/
https://www.ncbi.nlm.nih.gov/pubmed/29686836
http://dx.doi.org/10.1093/jscr/rjy068
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