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Quality assurance of rifampicin-containing fixed-drug combinations in South Africa: dosing implications

SETTING: Rifampicin (RMP) drives treatment response in drug-susceptible tuberculosis. Low RMP concentrations increase the risk of poor outcomes, and drug quality needs to be excluded as a contributor to low RMP exposure. OBJECTIVES AND DESIGN: We performed an open-label, three-way cross-over study o...

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Detalles Bibliográficos
Autores principales: Court, R., Chirehwa, M. T., Wiesner, L., Wright, B., Smythe, W., Kramer, N., McIlleron, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union Against Tuberculosis and Lung Disease 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905389/
https://www.ncbi.nlm.nih.gov/pubmed/29663959
http://dx.doi.org/10.5588/ijtld.17.0697