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Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity

BACKGROUND: Sarcopenia has been associated with reduced physical activity (PA). We aimed to determine if sarcopenia, and specific components of muscle size, function, and physical performance, are associated with high impacts achieved during habitual PA, as these are related to bone strength in comm...

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Autores principales: Hartley, April, Gregson, Celia L, Hannam, Kimberly, Deere, Kevin C, Clark, Emma M, Tobias, Jon H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905580/
https://www.ncbi.nlm.nih.gov/pubmed/29182712
http://dx.doi.org/10.1093/gerona/glx223
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author Hartley, April
Gregson, Celia L
Hannam, Kimberly
Deere, Kevin C
Clark, Emma M
Tobias, Jon H
author_facet Hartley, April
Gregson, Celia L
Hannam, Kimberly
Deere, Kevin C
Clark, Emma M
Tobias, Jon H
author_sort Hartley, April
collection PubMed
description BACKGROUND: Sarcopenia has been associated with reduced physical activity (PA). We aimed to determine if sarcopenia, and specific components of muscle size, function, and physical performance, are associated with high impacts achieved during habitual PA, as these are related to bone strength in community-dwelling older women. METHODS: Participants were older women from the Cohort of Skeletal Health in Bristol and Avon. We defined sarcopenia using the EWGSOP criteria. Lower limb peak muscle power and force were assessed using Jumping Mechanography (JM). High vertical impacts were assessed by tri-axial accelerometry (at least 1.5g above gravity). Cross-sectional associations were analyzed by linear regression, adjusting for age, height and weight (or fat mass for models including appendicular lean mass index), comorbidities, smoking, alcohol, and Index of Multiple Deprivation. RESULTS: Our analyses included 380 participants, with mean age 76.7 (SD 3.0) years; 242 (64%) also completed JM. In age-adjusted analysis, a negative relationship was observed between severity of sarcopenia and high, but not medium or low, impacts (p = .03 for trend). Regarding components of sarcopenia underlying this relationship, multivariable analyses revealed that gait speed (β 1.47 [95% CI 1.14, 1.89], [β-1] reflects the proportionate increase in high impacts per SD increase in exposure) and peak force (1.40 [1.07, 1.84]) were independently associated with high impacts. CONCLUSIONS: Older women with sarcopenia experienced fewer bone-strengthening high impacts than those with presarcopenia or without sarcopenia. To increase bone strengthening activity in older women, interventions need to improve both lower limb muscle force and walking speed.
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spelling pubmed-59055802018-04-23 Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity Hartley, April Gregson, Celia L Hannam, Kimberly Deere, Kevin C Clark, Emma M Tobias, Jon H J Gerontol A Biol Sci Med Sci The Journal of Gerontology: Medical Sciences BACKGROUND: Sarcopenia has been associated with reduced physical activity (PA). We aimed to determine if sarcopenia, and specific components of muscle size, function, and physical performance, are associated with high impacts achieved during habitual PA, as these are related to bone strength in community-dwelling older women. METHODS: Participants were older women from the Cohort of Skeletal Health in Bristol and Avon. We defined sarcopenia using the EWGSOP criteria. Lower limb peak muscle power and force were assessed using Jumping Mechanography (JM). High vertical impacts were assessed by tri-axial accelerometry (at least 1.5g above gravity). Cross-sectional associations were analyzed by linear regression, adjusting for age, height and weight (or fat mass for models including appendicular lean mass index), comorbidities, smoking, alcohol, and Index of Multiple Deprivation. RESULTS: Our analyses included 380 participants, with mean age 76.7 (SD 3.0) years; 242 (64%) also completed JM. In age-adjusted analysis, a negative relationship was observed between severity of sarcopenia and high, but not medium or low, impacts (p = .03 for trend). Regarding components of sarcopenia underlying this relationship, multivariable analyses revealed that gait speed (β 1.47 [95% CI 1.14, 1.89], [β-1] reflects the proportionate increase in high impacts per SD increase in exposure) and peak force (1.40 [1.07, 1.84]) were independently associated with high impacts. CONCLUSIONS: Older women with sarcopenia experienced fewer bone-strengthening high impacts than those with presarcopenia or without sarcopenia. To increase bone strengthening activity in older women, interventions need to improve both lower limb muscle force and walking speed. Oxford University Press 2018-04 2017-11-22 /pmc/articles/PMC5905580/ /pubmed/29182712 http://dx.doi.org/10.1093/gerona/glx223 Text en © The Author(s) 2017. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle The Journal of Gerontology: Medical Sciences
Hartley, April
Gregson, Celia L
Hannam, Kimberly
Deere, Kevin C
Clark, Emma M
Tobias, Jon H
Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity
title Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity
title_full Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity
title_fullStr Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity
title_full_unstemmed Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity
title_short Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity
title_sort sarcopenia is negatively related to high gravitational impacts achieved from day-to-day physical activity
topic The Journal of Gerontology: Medical Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905580/
https://www.ncbi.nlm.nih.gov/pubmed/29182712
http://dx.doi.org/10.1093/gerona/glx223
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