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Global proteomics profiling improves drug sensitivity prediction: results from a multi-omics, pan-cancer modeling approach

MOTIVATION: Proteomics profiling is increasingly being used for molecular stratification of cancer patients and cell-line panels. However, systematic assessment of the predictive power of large-scale proteomic technologies across various drug classes and cancer types is currently lacking. To that en...

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Detalles Bibliográficos
Autores principales: Ali, Mehreen, Khan, Suleiman A, Wennerberg, Krister, Aittokallio, Tero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905617/
https://www.ncbi.nlm.nih.gov/pubmed/29186355
http://dx.doi.org/10.1093/bioinformatics/btx766