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Phase II Study of Panitumumab in RAS Wild‐Type Metastatic Adenocarcinoma of Small Bowel or Ampulla of Vater

LESSONS LEARNED. Panitumumab has no clinical activity in metastatic RAS wild‐type small bowel adenocarcinoma (SBA) and ampullary adenocarcinoma (AAC), possibly due to the foregut and midgut derivation of small bowel and ampulla. These results, along with findings from genomic characterization of SBA...

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Detalles Bibliográficos
Autores principales: Gulhati, Pat, Raghav, Kanwal, Shroff, Rachna, Varadhachary, Gauri, Javle, Milind, Qiao, Wei, Wang, Huamin, Morris, Jeffrey, Wolff, Robert, Overman, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905687/
https://www.ncbi.nlm.nih.gov/pubmed/29259073
http://dx.doi.org/10.1634/theoncologist.2017-0568