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Silica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells

INTRODUCTION: Recently, the focus of oncological research has been on the optimization of therapeutic strategies targeted at malignant diseases. Nanomedicine utilizing silicon dioxide nanoparticles (SiNPs) is one such strategy and is rapidly developing as a promising tool for cancer diagnosis, imagi...

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Detalles Bibliográficos
Autores principales: Kusaczuk, Magdalena, Krętowski, Rafał, Naumowicz, Monika, Stypułkowska, Anna, Cechowska-Pasko, Marzanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905826/
https://www.ncbi.nlm.nih.gov/pubmed/29695906
http://dx.doi.org/10.2147/IJN.S158393